Why do I have mental health symptoms?

Mental distress is NOT “all in the head”.
Mental health is often the canary in the coal mine, signalling other co-morbidities.

When the body’s natural defence systems stop working properly, this can alter normal metabolic processes with symptoms showing changes in highly active brain cells earlier than in other cells in the body.

Mental health and behavioural changes, from mild to severe, are often the first signs of cellular damage.

Targeted blood and urine tests direct individualised treatment and support all current care guidelines for mental health. These test results empower both patient and practitioner to understand the issues and work together to reduce cellular damage.

Does it work? YES.

Veteran with 20 years of PTSD. After pathology changed his treatment, a few weeks into his treatment program, is amazed to start to feel “normal” at last.

Understanding the origin of your mental health symptoms

Mental health symptoms are often indicative of underlying biological imbalances. We would like to share our findings and encourage you to consider incorporating these insights into your mental health journey.

The Body’s three defence mechanisms:

1. Fight or Flight Mechanism:

  • The adrenal surge during a fear response releases glucose to energise muscles and the brain, simultaneously shutting down non-essential functions like bile flow and digestion.
  • Chronic or repetitive stress can prevent the body from returning to a resting state and recover, leading to prolonged dysfunction of bile flow and gut functions.

2. Inflammation and Repair:

  • An inflammatory response is essential for the body to repair from injury or infection, but can become problematic if excessive or prolonged.
  • Chronic inflammation can trigger unquenched oxidative stress.

3. Oxidative Stress Signalling:

  • ROS/RNS, in small numbers, signal messages to the rest of the body.
  • All systems in the body need to be balanced for proper function. When they don’t have enough resources, it affects normal metabolism. Reactive oxygen and nitrogen species need electrons to be neutralized; without this, they cause damage to cells.

Using hydrogen peroxide as the example of unquenched Reactive Oxygen Species (ROS).

Hydrogen Peroxide is the ROS most associated with mental health symptoms:

  • To prevent cellular damage, quenching of hydrogen peroxide by Cu.Zn-SOD and Fe.-Catalase firstly requires adequate copper and zinc and iron levels (and microlevels of selenium and manganese).
  • Failure to manage reactive oxygen species (ROS) leads to ongoing cellular damage, particularly in the brain due to the brain’s high metabolic rate and lipid content.
  • Hydrogen peroxide, in excess, can restrict methyl groups and this inhibited methylation can reduce DNA protection.
  • These impaired metabolic processes can potentially induce genetic changes that may be passed on to offspring.
  • Timely intervention is crucial to prevent cellular and epigenetic changes.

Precision Medicine:
Importance of Initial and Regular Testing for Mental Health Symptoms:

Just as initial fitness assessments are crucial to tailor a workout plan to an individual’s needs, initial testing is vital to understanding a patient’s unique biochemical starting point. Regular testing helps monitor progress and adapt treatment plans to ensure the desired health outcomes. This approach provides a clearer picture of the patient’s physiological state and allows for more precise and effective interventions.

Next Steps:

  1. Ask a GP for a request form for the Core Pathology Tests.
  2. Make an appointment with a Bio Balance Health trained practitioner to review your test results and symptoms, and develop an individualised treatment plan.
  3. Re-assess your progress with follow-up testing after 3 months of treatment.  This allows tweaking of your ongoing treatment plan for optimal health.

References: Mental health symptoms and oxidative stress

The following list of research studies is a glimpse into some of the research exploring the relationship between mental health symptoms and oxidative stress:

  • Several lines of antioxidant defense against oxidative stress: antioxidant enzymes, nano materials with multiple enzyme-mimicking activities, and low-molecular-weight antioxidants.
    Archives of Toxicology 98:1323-1367.
    Jomova, K. Alomar, S. Alwasel, S. Nepovimova, E. Kuca, K. Valko, M. (14 March, 2024).

Bio Balance Health has actively supported and funded the following research papers:

Dr Fryar-Williams’ work has developed an above 90% statistical probability of diagnosis of certain schizophrenic conditions by using a combination of biomarkers.

  • Biomarker Case-Detection and Prediction with Potential for Functional Psychosis Screening: Development and Validation of a Model Related to Biochemistry, Sensory Neural Timing and End Organ Performance.
    https://www.ncbi.nlm.nih.gov/pubmed/27148083
    Fryar-Williams S, Strobel JE.
  • Fundamental Role of Methylenetetrahydrofolate Reductase 677 C → T Genotype and Flavin Compounds in Biochemical Phenotypes for Schizophrenia and Schizoaffective Psychosis
    Fryar-Williams S, Strobel JE.
    https://www.ncbi.nlm.nih.gov/pubmed/27148083

This study demonstrated that Micronutrients can reduce violent behaviour:

  • Micronutrient Therapy for Violent Aggressive Male Youth
    Jessica L. Hambly, MPharm (Hons),1 Kelly Francis, MBBS, FRACGP,2 Sohil Khan, PhD,1,3 Kristen S. Gibbons, PhD, AStat,3 William J. Walsh, PhD,4 Brett Lambert, MAppSc,5 Chris Testa, BPharm, BBus,6 and Alison Haywood, PhD1,3
    https://www.ncbi.nlm.nih.gov/pubmed/28481642

Epigenetic modifications may play a major role in schizophrenia pathophysiology:

The study demonstrated that patients who followed the program had an average of 2 days hospitalisation compared to 22 days for those who did not follow the program:

Better Health Outcomes for Mental Health Patients is Our Mission

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