Schizophrenia Articles


Fundamental role of Methylenetetrahydrofolate reductase 677 c ? T genotype and Flavin compounds in Biochemical Phenotypes for schizophrenia and schizoaffective Psychosis

The Mental Health Biomarker Project (2010–2016) explored variables for psychosis in schizophrenia and schizoaffective disorder. Blood samples from 67, highly characterized symptomatic cases and 67 gender and age matched control participants were analyzed for methyl tetrahydrofolate reductase (MTHFR) 677C ? T gene variants and for vitamin B6, B12 and D, folate, unbound copper, zinc cofactors for enzymes in the methylation cycle, and related catecholamine pathways.

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Biomarker case-Detection and Prediction with Potential for Functional Psychosis screening: Development and Validation of a Model related to Biochemistry, sensory neural Timing & end Organ Performance

The Mental Health Biomarker Project aimed to discover case-predictive biomarkers for functional psychosis. In a retrospective, cross-sectional study, candidate marker results from 67 highly characterized symptomatic participants were compared with results from 67 gender- and age-matched controls.

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Biomarkers of a five-domain translational substrate for schizophrenia and schizoaffective psychosis

The Mental Health Biomarker Project (2010-2014) selected commercial biochemistry markers related to monoamine synthesis and metabolism and measures of visual and auditory processing performance.

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N-acetylcysteine in psychiatry:current therapeutic evidence and potential mechanisms of action

Review Paper

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Clinical Trials of N-acetylcysteine in psychiatry and neurology

A systematic review

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Beneficial effects of N-acetylcysteine in treatment resistant schizophrenia

Case Report

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An emerging role of cGMP in treatment of Schizophrenia

Schizophrenia Research

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Meta-Analysis of Oxidative Stress in Schizophrenia

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A potential interaction between COMT and MTHFR genetic variants in Han Chinese patients with bipolar II disorder

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Specific and common genes implicated across major mental disorders: A review of meta-analysis studies*

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Reduced folic acid, vitamin B12 and docosahexaenoic acid and increased homocysteine and cortisol in never-medicated schizophrenia patients: Implications for altered one-carbon metabolism

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Homocysteine levels in schizophrenia and affective disorders—focus on cognition

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Methylenetetrahydrofolate Reductase (MTHFR) Genetic Polymorphisms and Psychiatric Disorders: A HuGE Review

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Nutritional interventions for the adjunctive treatment of schizophrenia: a brief review

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Efficacy and tolerability of minocycline augmentation therapy in schizophrenia: a systematic review and meta-analysis of randomized controlled trials

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Methylenetetrahydrofolate reductase (MTHFR) genetic polymorphisms and psychiatric disorders: a HuGE review.

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Randomized Multicenter Investigation of Folate Plus Vitamin B12 Supplementation in Schizophrenia

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Genetic Variation Throughout the Folate Metabolic Pathway Influences Negative Symptom Severity in Schizophrenia

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